{"id":2358,"date":"1980-12-30T09:24:37","date_gmt":"1980-12-30T00:24:37","guid":{"rendered":"https:\/\/www.heimat-ltd.com\/en\/?p=2358"},"modified":"2022-11-09T09:26:25","modified_gmt":"2022-11-09T00:26:25","slug":"1980-practitioner","status":"publish","type":"post","link":"https:\/\/www.heimat-ltd.com\/en\/information\/pub\/1980-practitioner.html","title":{"rendered":"Perna canaliculus in the treatment of arthritis"},"content":{"rendered":"<div class=\"details_box\">\r\n  <h2>Introduction<\/h2>\r\n  <p>Arthritis in one or other of its several forms continues to be a major cause of disability in the UK. Although many non-steroidal anti-inflammatory drugs are now available, none is wholly effective, and side effects remain a problem. The search for a safer and more effective anti-inflammatory agent therefore continues.<\/p>\r\n  <p>Five years ago, a preparation of the New Zealand green lipped mussel, Perna canaliculus, came to our notice, and a preliminary therapeutic trial was carried out in 86 patients, 55 with rheumatoid arthritis and 31 with osteoarthritis. The patients were treated for periods ranging from six months to 4.5 years: 67% of those with rheumatoid arthritis and 35% of those with osteoarthritis benefited. Toxic effects were uncommon and generally mild.<\/p>\r\n  <p>In order to evaluate the efficacy of this preparation more fully, it was decided to carry out a carefully controlled double-blind trial on a similar group of patients. This second trial was also designed to include a greater number of patients suffering from osteoarthritis to obtain a more accurate assessment of the effect of the agent in this condition.<\/p>\r\n<\/div>","protected":false},"excerpt":{"rendered":"Introduction Arthritis in one or other of its several forms continues to be a major cause of disability in the UK. Although many non-steroidal anti-inflammatory drugs are now available, none is wholly effective, and side effects remain a problem. The search for a safer and more effective anti-inflammatory agent therefore continues. Five years ago, a preparation of the New Zealand green lipped mussel, Perna canaliculus, came to our notice, and a preliminary therapeutic trial was carried out in 86 patients, 55 with rheumatoid arthritis and 31 with osteoarthritis. The patients were treated for periods ranging from six months to 4.5 years: 67% of those with rheumatoid arthritis and 35% of [&hellip;]","protected":false},"author":98,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[73],"tags":[],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/posts\/2358"}],"collection":[{"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/users\/98"}],"replies":[{"embeddable":true,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/comments?post=2358"}],"version-history":[{"count":1,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/posts\/2358\/revisions"}],"predecessor-version":[{"id":2359,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/posts\/2358\/revisions\/2359"}],"wp:attachment":[{"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/media?parent=2358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/categories?post=2358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.heimat-ltd.com\/en\/wp-json\/wp\/v2\/tags?post=2358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}