Cherry Blossom (Sakura) Extract

Cherry blossom flowers are familiar to the Japanese, and some species of the flowers soaked in salty vinegar are used as processed foods. Sakura-cha (salted cherry blossom tea) is a Japanese tea that is traditionally served at celebrations such as wedding ceremonies. The production of Sakura-cha includes the immersion of cherry blossom flowers in Japanese plum vinegar, and through this process, the byproduct (plum vinegar extract of cherry blossom) is obtained. The experiment demonstrated that plum vinegar extract of cherry blossom had antioxidant activity. The plum vinegar extract of cherry blossom had a greater superoxide anion scavenging activity compared with red wine, which is a well-known strong antioxidant. Liquid chromatography-mass spectrometry analysis showed that cyanidin-3-glucoside, cyanidin-3-rutinoside, and caffeic acid were the major components in the phenolic extract prepared from plum vinegar extract of cherry blossom, and they possessed superoxide anion scavenging activity.

Skin aging due to oxidative stress can cause a rusty coloured appearance. The probable cause for this is glycation stress related aging of skin due to the accumulation of Advanced Glycation End Products (AGEs). Recent reports have shown that AGEs formed in the dermis cause skin yellowing. In addition to the effects of exposure to excessive ultra violet radiation in sunlight, AGEs have been found to accumulate in the epidermis. ultimately reducing skin elasticity, causing dullness and a yellowish discoloration. IN addition to the inhibition of melanin production, anti-glycation activity is considered to be an important anti-aging approach for the maintenance of healthy skin texture. Extracts prepared from cherry blossom (Prunus lannesiana) flowers (CBE) have been shown to suppress AGE production and AGE-induced fibroblast apoptosis (programmed cell death of tissue building cells). In this way Cherry blossom flower extracts may be effective against age related skin damage.

A placebo-controlled randomized single-blind parallel group comparative study found that foods containing lingonberry extract and cherry blossom extract, in the form of chewable tablets containing citric acid and calcium had significant anti-glycation activity. The product was also shown to be safe for human consumption. These results suggest that a food item containing lingonberry extract, cherry blossom extract, citric acid and calcium may mitigate glycation stress and suppress the accumulation of AGEs in the skin.

References
  1. Matsuura R; Moriyama H; Takeda N; Yamamoto K; Morita Y; Shimamura T; Ukeda H. Determination of antioxidant activity and characterization of antioxidant phenolics in the plum vinegar extract of cherry blossom (Prunus lannesiana). J Agric Food Chem. 2008 Jan 23, 56(2):544-549. Epub 2007 Dec 20.
  2. Shimoda H; Nakamura S; Morioka M; Tanaka J; Matsuda H; Yoshikawa M. Effect of Cinnamoyl and Flavonol Glucosides Derived from Cherry Blossom Flowers on the Production of Advanced Glycation End Products (AGEs) and AGE-induced Fibroblast Apoptosis. Phytother Res. 2011 Feb 10. doi: 10.1002/ptr.3423.
  3. Yoshikazu Yonei; Masayuki Yagi; Mari Ogura; Haruhi Sugimura. Anti-Glycation Activity and Safety of Foods Containing Lingonberry Extract and Cherry Blossom Extract and Chewable Tablets Containing Citric Acid and Calcium −A Placebo-Controlled Randomized Single-Blind Parallel Group Comparative Study. Anti-Aging Medicine 10(2):21-35, 2013.
  4. Yook HS, Kim KH, Park JE, Shin HJ. Antioxidative and antiviral properties of flowering cherry fruits (Prunus serrulata L. var. spontanea). Am J Chin Med. 2010;38(5):937-48.
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Raw materials, OEM and PB option at Heimat Co., Japan Ltd
APCGCT: Asia Pacific Consortium of Gene and Cell Therapy
株式会社遺伝子治療研究所
  • Raw materials, OEM and PB option at Heimat Co., Japan Ltd
  • APCGCT: Asia Pacific Consortium of Gene and Cell Therapy
    株式会社遺伝子治療研究所